Drug Information
Drug General Information | Top | |||
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Drug ID |
D00XNY
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Former ID |
DNC000066
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Drug Name |
4,5,6,7-tetrahydroisoxazolo-[5,4-c]-pyridin-3-ol
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Synonyms |
THIP hydrochloride; GABOXADOL HYDROCHLORIDE; 85118-33-8; UNII-478RVH3TVD; 478RVH3TVD; 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride; 4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HCL, GABOXADOL-HCL; SR-01000075651; EINECS 285-687-7; THIP NIEaNI; THIP HCl; AC1NWAX4; Gaboxadol (hydrochloride); MLS002154080; SPECTRUM1503648; CHEMBL1255746; CTK8G3449; DTXSID90234251; AOB5024; MolPort-006-141-665; MolPort-003-666-496; HMS1571C05; Pharmakon1600-01503648; BCP16610; Tox21_501233; BN0520; NSC759585; CCG-39368
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C6H9ClN2O2
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Canonical SMILES |
C1CNCC2=C1C(=O)NO2.Cl
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InChI |
1S/C6H8N2O2.ClH/c9-6-4-1-2-7-3-5(4)10-8-6;/h7H,1-3H2,(H,8,9);1H
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InChIKey |
ZDZDSZQYRBZPNN-UHFFFAOYSA-N
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CAS Number |
CAS 85118-33-8
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PubChem Compound ID | ||||
PubChem Substance ID |
8150029, 14916324, 17405787, 24278200, 26612513, 26679397, 26747696, 50107170, 50107171, 50107172, 53778339, 56463588, 57364933, 57654649, 76085763, 85089911, 91011607, 92125949, 92303164, 103913865, 114069547, 123096308, 124637208, 125542250, 126604520, 135265810, 137118832, 143503055, 144076063, 162091441, 163138343, 163565187, 163778790, 188889429, 198947589, 219571553, 223958936, 241115389, 241149237, 241181907, 252401138, 252450820
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Target and Pathway | Top | |||
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Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Agonist | [1] |
References | Top | |||
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REF 1 | Reduction in potency of selective gamma-aminobutyric acidA agonists and diazepam in CA1 region of in vitro hippocampal slices from chronic flurazepam-treated rats. J Pharmacol Exp Ther. 1992 Jul;262(1):204-11. |
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