Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00WSN
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| Former ID |
DNC008057
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| Drug Name |
N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide
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| Synonyms |
CHEMBL251369; N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide; AC1MH48W; MLS001162447; SCHEMBL13148062; cid_2996093; N-[2-(morpholin-4-yl)phenyl]-5-nitrofuran-2-carboxamide; MolPort-002-305-194; HMS2967E08; ZINC4842600; STK355602; BDBM50223675; AKOS000458368; MCULE-3330873928; SMR000670465; VU0465060-1; N-(2-morpholin-4-ylphenyl)-5-nitro-2-furamide; AP-970/43481542; N-[2-(4-morpholinyl)phenyl]-5-nitro-2-furamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H15N3O5
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| Canonical SMILES |
C1COCCN1C2=CC=CC=C2NC(=O)C3=CC=C(O3)[N+](=O)[O-]
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| InChI |
1S/C15H15N3O5/c19-15(13-5-6-14(23-13)18(20)21)16-11-3-1-2-4-12(11)17-7-9-22-10-8-17/h1-6H,7-10H2,(H,16,19)
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| InChIKey |
BIQWNNXDPVEAPZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Granulocyte colony-stimulating factor receptor (G-CSF-R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Pathways in cancer | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4. | |||
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