Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00WOT
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| Former ID |
DIB008941
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| Drug Name |
CDP-850
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| Synonyms |
VLA-4, Celltech; Anti-E-selectin antibody, Celltech
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| Drug Type |
Antibody
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 2 | [1] | |
| Company |
UCB Celltech
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P-selectin (SELP) | Target Info | . | [2] |
| KEGG Pathway | Cell adhesion molecules (CAMs) | |||
| Malaria | ||||
| Staphylococcus aureus infection | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| amb2 Integrin signaling | ||||
| Reactome | Platelet degranulation | |||
| Cell surface interactions at the vascular wall | ||||
| WikiPathways | Human Complement System | |||
| Spinal Cord Injury | ||||
| Cell surface interactions at the vascular wall | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007242) | |||
| REF 2 | WO patent application no. 2001,0276,21, Competitive inhibition elisa for antibody detection. | |||
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