Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00VHS
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| Former ID |
DNC013860
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| Drug Name |
4-(5-(4-Hydroxyphenyl)isothiazol-4-yl)phenol
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C15H11NO2S
|
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| Canonical SMILES |
C1=CC(=CC=C1C2=C(SN=C2)C3=CC=C(C=C3)O)O
|
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| InChI |
1S/C15H11NO2S/c17-12-5-1-10(2-6-12)14-9-16-19-15(14)11-3-7-13(18)8-4-11/h1-9,17-18H
|
|||
| InChIKey |
OCBISDMDUBGFSN-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase 1 (COX-1) | Target Info | Inhibitor | [1] |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Platelet activation | ||||
| Serotonergic synapse | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Arachidonic acid metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, *OH scavenging and anti-adhesive activities. Bioorg Med Chem. 2009 Jan 15;17(2):558-68. | |||
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