Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00UOQ
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| Former ID |
DIB010530
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| Drug Name |
PAT-SC1
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| Synonyms |
SC-1; Adjuvant therapy (gastric cancer), University of Wurzburg; SC-1 (gastric cancer), CAT; SC-1 (gastric cancer), Debiopharm; SC-1 (gastric cancer), Patrys; SC-1 (stomach cancer), OncoMab
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| Drug Type |
Antibody
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| Indication | Gastric adenocarcinoma [ICD-11: 2B72; ICD-9: 151] | Phase 1/2 | [1] | |
| Company |
Universitat Wurzburg
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Complement decay-accelerating factor (CD55) | Target Info | . | [2] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Hematopoietic cell lineage | ||||
| Viral myocarditis | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| FSH Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Reactome | Class B/2 (Secretin family receptors) | |||
| Regulation of Complement cascade | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Complement Activation, Classical Pathway | ||||
| Human Complement System | ||||
| GPCR ligand binding | ||||
| Complement cascade | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013314) | |||
| REF 2 | Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1. Oncol Rep. 2014 Mar;31(3):1059-66. | |||
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