Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00SCI
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| Former ID |
DIB020354
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| Drug Name |
MI-3
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| Synonyms |
MI-3; MI-3 (Menin-MLL Inhibitor); 4-(4-(5,5-Dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-isopropylthieno[2,3-d]pyrimidine; GTPL8103; CHEMBL3696180; SCHEMBL12789955; MolPort-035-789-713; BDBM152232; BCP11052; EX-A2098; s7619; ZINC95641929; AKOS030526376; CS-0772; SB19342; NCGC00386410-02; HY-15223; BC600609; US8993552, 67; 1-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-4-[6-(propan-2-yl)thieno[2,3-d]pyrimidin-4-yl]piperazine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C18H25N5S2
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| Canonical SMILES |
CC(C)C1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C
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| InChI |
1S/C18H25N5S2/c1-12(2)14-9-13-15(20-11-21-16(13)24-14)22-5-7-23(8-6-22)17-19-10-18(3,4)25-17/h9,11-12H,5-8,10H2,1-4H3
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| InChIKey |
FUGQNAUKABUDQI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nat Chem Biol. 2012 Jan 29;8(3):277-84. | |||
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