Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00RXS
|
|||
| Former ID |
DNC000193
|
|||
| Drug Name |
AMD3101
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Canonical SMILES |
C1=NC2=C(C1C3C(C(C(N3)CO)O)O)NC(=NC2=O)N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | C-X-C chemokine receptor type 6 (CXCR6) | Target Info | Antagonist | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Chemokine signaling pathway | ||||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Reactome | Chemokine receptors bind chemokines | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Peptide GPCRs | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Opportunities and challenges in targeting HIV entry. Curr Opin Pharmacol. 2002 Oct;2(5):529-33. | |||
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