Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00RWW
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| Former ID |
DIB004432
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| Drug Name |
Fexinidazole
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| Synonyms |
Fexinidazole (human African trypanosomiasis); Fexinidazole (African sleeping sickness), Drugs for Neglected Diseases initiative; Fexinidazole (HAT), Drugs for Neglected Diseases initiative; Fexinidazole (human African trypanosomiasis), Drugs for Neglected Diseases initiative
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| Drug Type |
Small molecular drug
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| Indication | African trypanosomiasis [ICD-11: 1F51; ICD-10: B56, B56.9; ICD-9: 86.5] | Approved | [1] | |
| Trypanosomiasis [ICD-11: 1D51-1F53; ICD-10: B56-B57; ICD-9: 086.5-086] | Phase 2/3 | [2] | ||
| Company |
Sanofi/DNDi
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| Structure |
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Download2D MOL |
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| Formula |
C12H13N3O3S
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| Canonical SMILES |
CN1C(=CN=C1COC2=CC=C(C=C2)SC)[N+](=O)[O-]
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| InChI |
1S/C12H13N3O3S/c1-14-11(13-7-12(14)15(16)17)8-18-9-3-5-10(19-2)6-4-9/h3-7H,8H2,1-2H3
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| InChIKey |
MIWWSGDADVMLTG-UHFFFAOYSA-N
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| CAS Number |
CAS 59729-37-2
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2021. Application Number: 214429. | |||
| REF 2 | ClinicalTrials.gov (NCT02169557) Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal Study. U.S. National Institutes of Health. | |||
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