Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00NVO
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| Former ID |
DIB009490
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| Drug Name |
Flezelastine
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| Synonyms |
D-18024
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Phase 2 | [1] | |
| Company |
ASTA Medica AG
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H30FN3O
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| Canonical SMILES |
C1CC(CCN(C1)CCC2=CC=CC=C2)N3C(=O)C4=CC=CC=C4C(=N3)CC5=CC=C(C=C5)F
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| InChI |
1S/C29H30FN3O/c30-24-14-12-23(13-15-24)21-28-26-10-4-5-11-27(26)29(34)33(31-28)25-9-6-18-32(20-17-25)19-16-22-7-2-1-3-8-22/h1-5,7-8,10-15,25H,6,9,16-21H2
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| InChIKey |
HQFSNUYUXXPVKL-UHFFFAOYSA-N
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| CAS Number |
CAS 135381-77-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | IL-1 synthesis/release (IL-1 synth/rele) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effects of flezelastine and its enantiomers on LPS-induced IL-1 beta generation in vitro and LPS-induced pyrexia in vivo. Agents Actions. 1994 Mar;41(1-2):99-100. | |||
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