Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00MHP
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| Former ID |
DIB003985
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| Drug Name |
SR-2640
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| Synonyms |
SR 2640; SR-2640; SR 2640 Hydrochloride; 105350-26-3; CHEMBL18132; SR2640; Benzoic acid, 2-[[3-(2-quinolinylmethoxy)phenyl]amino]-; QMPB; Benzoic acid, 2-((3-(2-quinolinylmethoxy)phenyl)amino)-; SR-01000076219; Tocris-1804; Lopac-S-7690; AC1L2TN9; Lopac0_001079; 2-(3-(2-Quinolylmethoxy)phenylamino)benzoic acid; MLS002153402; cid_128355; GTPL3329; SCHEMBL9119607; CTK8F0698; CHEBI:104023; HMS3263G20; HMS2236C03; ZINC596951; HMS3373N15; Tox21_501079; BDBM50006798; AKOS030239522; LP01079; CCG-205156; NCGC00015965-02; NCGC00015965-04
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Phase 2 | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C23H18N2O3
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| Canonical SMILES |
C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=CC(=C3)NC4=CC=CC=C4C(=O)O
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| InChI |
1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)
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| InChIKey |
LMPZHLXYBWGGNT-UHFFFAOYSA-N
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| CAS Number |
CAS 105350-26-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
6882074, 10242019, 11111817, 11114220, 15326271, 17405635, 24278799, 29307425, 47796132, 50104959, 50104960, 53778185, 56463195, 57342540, 78505573, 85231233, 85787630, 90341565, 92303173, 103183011, 103920116, 104367938, 121361904, 124750219, 124801411, 124881485, 124881486, 124881487, 125541609, 128510997, 135084480, 162247809, 163125610, 163565033, 178100361, 178127217, 179149529, 184536699, 184600307, 204359780, 223532809, 234558594, 252345587
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| ChEBI ID |
CHEBI:104023
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukotriene receptor (LTR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3329). | |||
| REF 2 | Effect of the leukotriene LTD4/LTE4 antagonist, SR 2640, in ulcerative colitis: an open clinical study. Prostaglandins Leukot Essent Fatty Acids. 1991 Mar;42(3):181-4. | |||
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