Drug Information
Drug General Information | Top | |||
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Drug ID |
D00KRL
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Former ID |
DNC008385
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Drug Name |
Ethyl 4-(1-benzyl-1H-indazol-3-yl)benzoate
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Synonyms |
YD-3; CHEMBL125021; SCHEMBL363569; GTPL9458; LPROLPQTWKDPNU-UHFFFAOYSA-N; BDBM50024254; 1-benzyl-3-(4'-ethoxycarbonylphenyl)indazole; ethyl 4-(1-benzyl-1h-indazol-3-yl)-benzoate
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C23H20N2O2
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Canonical SMILES |
CCOC(=O)C1=CC=C(C=C1)C2=NN(C3=CC=CC=C32)CC4=CC=CC=C4
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InChI |
1S/C23H20N2O2/c1-2-27-23(26)19-14-12-18(13-15-19)22-20-10-6-7-11-21(20)25(24-22)16-17-8-4-3-5-9-17/h3-15H,2,16H2,1H3
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InChIKey |
LPROLPQTWKDPNU-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Proteinase activated receptor 4 (F2RL3) | Target Info | Inhibitor | [1] |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Platelet activation | ||||
Pathways in cancer | ||||
Panther Pathway | Blood coagulation | |||
Pathway Interaction Database | PAR4-mediated thrombin signaling events | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (q) signalling events | ||||
Thrombin signalling through proteinase activated receptors (PARs) | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
Thrombin signalling through proteinase activated receptors (PARs) | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Synthesis and antiplatelet activity of ethyl 4-(1-benzyl-1H-indazol-3-yl)benzoate (YD-3) derivatives. Bioorg Med Chem. 2008 Feb 1;16(3):1262-78. |
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