Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00IUD
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| Former ID |
DCL000853
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| Drug Name |
K-832
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| Synonyms |
10465-81-3; 1,1'-(Azodicarbonyl)-dipiperidine; AdDP; 1,1-(Azodicarbonyl)dipiperidine; 1,1'-(Azodicarbonyl)dipiperidine; diazene-1,2-diylbis(piperidin-1-ylmethanone); NSC356027; NSC 356027; (NE)-N-(piperidine-1-carbonylimino)piperidine-1-carboxamide; azodicarboxylic acid dipiperidine; (E)-diazene-1,2-diylbis(piperidin-1-ylmethanone); Azodicarboxylic acid dipiperidide; J-503690; SR-4077; (E)-diazene-1,2-diylbis(piperidin-1-yl methanone); SR 4077; PubChem19605; piperidyl (piperidylcarbonyl)diazenyl ketone; AC1Q5JWC; AC1NWBQ9
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| Drug Type |
Small molecular drug
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Phase 2 | [1] | |
| Company |
Kowa
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H19ClN2OS
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| Canonical SMILES |
CSC1=CC=C(C=C1)C2=NN(C(=O)C=C2C3=CC=C(C=C3)Cl)CC4=CC=CC=C4
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| InChI |
1S/C24H19ClN2OS/c1-29-21-13-9-19(10-14-21)24-22(18-7-11-20(25)12-8-18)15-23(28)27(26-24)16-17-5-3-2-4-6-17/h2-15H,16H2,1H3
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| InChIKey |
HEUAVAATAFEENP-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID |
464583, 613414, 3155755, 11737046, 14794979, 24847283, 24855495, 57364956, 78073057, 87562542, 91689078, 92251799, 92714853, 103816353, 114070596, 117570404, 118696472, 123918852, 126590593, 126629406, 126655168, 131293473, 135029934, 135594702, 135699801, 135716421, 136023032, 136991038, 137129991, 137293921, 143490313, 143858199, 151993405, 152237262, 162118884, 162179334, 162245416, 163386864, 163820396, 164791057, 172089883, 174559970, 179323313, 196107880, 204426604, 223259257, 223367347, 223377976, 249779977, 249791670
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin-1 (IL1) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for rheumatoid arthritis. Expert Opin Emerg Drugs. 2008 Mar;13(1):175-96. | |||
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