Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00IGI
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| Former ID |
DNC004971
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| Drug Name |
2-Amino-4-phosphono-butyric acid
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| Synonyms |
2-amino-4-phosphonobutanoic acid; 6323-99-5; DL-AP4; 20263-07-4; DL-2-Amino-4-phosphonobutyric acid; Butanoic acid, 2-amino-4-phosphono-; BRN 5255932; CHEMBL285843; BUTYRIC ACID, 2-AMINO-4-PHOSPHONO-; MFCD00013999; L-2-amino-4-phosphonobutyrate; Abu(P); SR-01000075414; L-2-amino-4-phosphobutyric acid; L-AP4 cpd, butyric; AC1Q6RPJ; 4-Amino Phosphonobutyrate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C4H10NO5P
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| Canonical SMILES |
C(CP(=O)(O)O)C(C(=O)O)N
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| InChI |
1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
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| InChIKey |
DDOQBQRIEWHWBT-UHFFFAOYSA-N
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| CAS Number |
CAS 6323-99-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Metabotropic glutamate receptor 8 (mGluR8) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Glutamatergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Metabotropic glutamate receptor group III pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | (2S,1'S,2'R,3'R)-2(2'-Carboxy-3'-hydroxymethylcyclopropyl)glycine-[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic ... Bioorg Med Chem Lett. 2005 Jan 17;15(2):349-51. | |||
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