Drug Information
Drug General Information | Top | |||
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Drug ID |
D00HUV
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Former ID |
DNC003771
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Drug Name |
[2-(1H-Benzoimidazol-4-yloxy)-ethyl]-benzyl-amine
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Synonyms |
CHEMBL89420; [2-(1H-Benzoimidazol-4-yloxy)-ethyl]-benzyl-amine; SCHEMBL8120489; BDBM50081111
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H17N3O
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Canonical SMILES |
C1=CC=C(C=C1)CNCCOC2=CC=CC3=C2N=CN3
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InChI |
1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-15-8-4-7-14-16(15)19-12-18-14/h1-8,12,17H,9-11H2,(H,18,19)
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InChIKey |
XQWCSGWUJUEAQM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Dopamine D2 receptor (D2R) | Target Info | Inhibitor | [1] |
Dopamine D3 receptor (D3R) | Target Info | Inhibitor | [1] | |
Dopamine D4 receptor (D4R) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Dopaminergic synapse | ||||
Rap1 signaling pathway | ||||
cAMP signaling pathway | ||||
Gap junction | ||||
Parkinson's disease | ||||
Cocaine addiction | ||||
Alcoholism | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Dopamine receptor mediated signaling pathway | ||||
Nicotine pharmacodynamics pathway | ||||
Reactome | Dopamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Nicotine Activity on Dopaminergic Neurons | ||||
GPCRs, Other | ||||
Hypothetical Network for Drug Addiction | ||||
Genes and (Common) Pathways Underlying Drug Addiction |
References | Top | |||
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REF 1 | New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D2 template. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2593-8. |
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