Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00GES
|
|||
| Former ID |
DPR000182
|
|||
| Drug Name |
JD-5037
|
|||
| Indication | Diabetic complication [ICD-11: 5A2Y] | Preclinical | [1] | |
| Obesity [ICD-11: 5B81; ICD-10: E66] | Preclinical | [1] | ||
| Company |
Jenrin Discovery Inc.
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C27H27Cl2N5O3S
|
|||
| Canonical SMILES |
CC(C)C(C(=O)N)N=C(NS(=O)(=O)C1=CC=C(C=C1)Cl)N2CC(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4
|
|||
| InChI |
1S/C27H27Cl2N5O3S/c1-17(2)24(26(30)35)31-27(33-38(36,37)22-14-12-21(29)13-15-22)34-16-23(18-6-4-3-5-7-18)25(32-34)19-8-10-20(28)11-9-19/h3-15,17,23-24H,16H2,1-2H3,(H2,30,35)(H,31,33)/t23-,24+/m1/s1
|
|||
| InChIKey |
GTCSIQFTNPTSLO-RPWUZVMVSA-N
|
|||
| CAS Number |
CAS 1392116-14-1
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Agonist | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| BDNF signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2011 Pipeline of Jenrin Discovery. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.