Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00CQT
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| Former ID |
DNC000554
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| Drug Name |
Dichloroallyl lawsone
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| Synonyms |
Dichloroallyl lawsone; Dichlorolapachol; Dichlorolawsone; Dichloroallyllawsone; Lawsone, dichlorallyl-; 36417-16-0; NSC 126771; NSC-126771; 2-Hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone; UNII-ZE2BI297KA; BRN 1977648; ZE2BI297KA; 1,4-Naphthoquinone, 2-(3,3-dichloroallyl)-3-hydroxy-; MLS002701983; 1,4-NAPHTHALENEDIONE, 2-(3,3-DICHLORO-2-PROPENYL)-3-HYDROXY-; NSC126771; 3-(3,3-Dichloroallyl)-2-hydroxy-1,4-naphthoquinone; AC1L5MNX; AC1Q3FFX; NCIMech_000041; Dichloroallyl lawsone (DCL); C13H8Cl2O3
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C13H8Cl2O3
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=C(C(=O)C2=O)CC=C(Cl)Cl)O
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| InChI |
1S/C13H8Cl2O3/c14-10(15)6-5-9-11(16)7-3-1-2-4-8(7)12(17)13(9)18/h1-4,6,16H,5H2
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| InChIKey |
LWQZLQISFLBSGW-UHFFFAOYSA-N
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| CAS Number |
CAS 36417-16-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity. J Biol Chem. 2002 Nov 1;277(44):41827-34. | |||
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