Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00AKV
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| Former ID |
DIB000211
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| Drug Name |
F-351
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| Synonyms |
Liver cirrhosis, Gene Networks International; Liver cirrhosis, Shanghai; Liver fibrosis therapy, Shanghai Genomics; Liver fibrosis, Gene Networks International; Liver fibrosis, Shanghai
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| Drug Type |
Small molecular drug
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| Indication | Liver disease [ICD-11: DB90-BD99] | Phase 2 | [1] | |
| Company |
GNI Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C12H11NO2
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| Canonical SMILES |
CC1=CN(C(=O)C=C1)C2=CC=C(C=C2)O
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| InChI |
1S/C12H11NO2/c1-9-2-7-12(15)13(8-9)10-3-5-11(14)6-4-10/h2-8,14H,1H3
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| InChIKey |
NETTXQJYJRFTFS-UHFFFAOYSA-N
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| CAS Number |
CAS 851518-71-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aminotransferase (AT) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020436) | |||
| REF 2 | Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus. J Bacteriol. 2000 Jul;182(14):4087-95. | |||
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